Abstract Given that hypoxia is a persistent physiological feature of many different solid tumors and a key driver for cancer malignancy, it is thought to be a major target in cancer treatment recently.Tumor-associated macrophages (TAMs) are the most abundant immune cells in the tumor microenvironment (TME), which have a large impact on tumor develo
The use Side Pull of contaminated water to irrigate crops by surface, sprinkler, or conventional drip irrigation represents a significant public health concern due to the presence of multiple microbial pathogens associated with gastrointestinal disease.In this study, Escherichia coli and MS2 bacteriophage were used as microbial surrogates to evalua
The finite-time barotropic instability problem is modified by Beverage Chilling Cubes investigating the impact of an anomalous (steady) forcing on the development of optimal initial perturbations.Although the model considered is linear, due to the nonlinear optimization procedure the addition of a forcing can influence the initial disturbance.In pa
Background: Diabetic retinopathy (DR) is a major cause of blindness globally.Sodium Glucose Cotransporter-2 (SGLT2) inhibitors have been demonstrated to exert cardiorenal protection in patients with diabetes.However, their potential beneficial effect on DR is less well studied.The aim of the present study was to determine the effects of the SGLT2 i
Understanding the factors that make people more likely to refuse vaccination against COVID-19 is crucial in order to design public health messages efficient in increasing vaccination rates.As COVID-19 creates risks of seriously damaging health effects, fear of this disease is as a significant determinant of vaccination intentions, as indicated by p